This year, the Emmys were hosted without a live crowd. Kimmel had viewers at home fooled in the beginning, using footage from previous award shows to create the effect of a live audience.
"Hello and welcome to the Pand-Emmys. It's great to finally see people again. Thank you for risking everything to be here...You know what they say, you can't have a virus without a host" said Kimmel in his opening monologue.
Nominees joined the Emmys from the comfort of their homes. Zendaya, who was nominated for 'best lead actress in a drama' had her family and team rallying behind her while she waited anxiously for the announcement to be made.
She was up against some tough competition, with actresses like Jennifer Aniston, Olivia Colman, Sandra Oh, Laura Linney, Jodie Comer.
In a matter of a few seconds, history had been made as Jimmy Kimmel announced Zendaya as the winner of the category.
“Thank you to the TV academy, to all of the other incredible women in this category, I admire you all so much."
She was taken back by her win, squeezing in an occasional "thank you" when she wasn't out of breath from shock.
"This is pretty crazy, I don't really cry," she said holding her new Emmy.
Zendaya gave a special thank you to Sam Levinson, creator of Euphoria.
"I'm so grateful that you trusted me with your story, and I hope I can continue to do you proud."
Euphoria is a coming of age show that follows the lives of teenagers as they find their identities and experience love, drugs, sex and everyday drama.
“I just want to say that there is hope in the young people out there...To all my peers out there doing the work in the streets: I see you, I admire you, I thank you,” said Zendaya before breaking out into a scream to celebrate her win one last time.